Synthesis of Spiro[indole-3,2′-pyrrole]triones by the Reaction of Pyrrolobenzoxazepinetriones with Enaminoketone
摘要
Abstract
The reaction of 3-aroylpyrrolo[1,2-a][4,1]benzoxazepine-1,2,4-triones with 3-(cyclohexylamino)-5,5-dimethylcyclohex-2-en-1-one afforded 3′-aroyl-1-cyclohexyl-4′-hydroxy-1′-[2-(hydroxymethyl)phenyl]-6,6-dimethyl-6,7-dihydrospiro[indole-3,2′-pyrrole]-2,4,5′(1H,1′H,5H)-triones. This reaction can be regarded as a new method of synthesis of spiro[indole-3,2′-pyrrole] derivatives.