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Synthesis of Methyl 2-O-Benzoyl-3,5-di-O-benzyl-α-L-talofuranoside

  • M. J. Khalikova,
  • U. A. Rozikov,
  • A. S. Skrylkova,
  • D. M. Egorov,
  • S. Sh. Safarov

摘要

Abstract

Methyl 2-O-benzoyl-3,5-di-O-benzyl-α-L-talofuranoside was synthesized from methyl 3,5-di-O-benzyl-1,2-O-isopropylidene-α-L-talofuranoside which was successively treated with 20% hydrochloric acid in aqueous methanol and benzoyl chloride in anhydrous pyridine. Prospects of using methyl 2-O-benzoyl-3,5-di-O-benzyl-α-L-talofuranoside for the synthesis of new modified nucleosides were demonstrated.