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Tetrazoles: Versatile Biomimetics of Peptides

  • H. S. Lalithamba,
  • G. Nagendra,
  • M. Ramya,
  • G. K. Prashanth

摘要

Abstract

The present communication reflects different approaches for the synthesis of tetrazole biomimetic replacement of carboxylic acid. Tetrazole is one among the many isosteres that represent the true replacement to carboxylic acid. Tetrazole tethered molecules exhibit many biological activities and catalytic activities in organic transformations. Synthetic methodologies for the construction of free tetrazole, substituted tetrazole, fused tetrazoles, etc., were substantiated that would offer a platform to encompass the researcher to avail complete information on the tetrazoles.