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Abstract <p>New functional derivatives of isobornylphenols containing a SCN group at the <i>para</i>-position of the benzene ring were synthesized. It was found that the nature of the solvent influences the reaction course. The use of polar aprotic solvents reduces the reaction time and increases the yield of the target product. The obtained thiocyanate derivatives of isobornylphenols exhibit antioxidant activity in various <i>in vitro</i> models.</p>

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Synthesis and Antioxidant Activity of Thiocyanate Derivatives of Isobornylphenols

  • 期刊论文

  • 发表日期：

    2026年5月30日

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  • Olga V. Shchukina,
  • Irina Yu. Chukicheva,
  • Lidiya I. Mazaletskaya,
  • Oksana G. Shevchenko,
  • Aleksandr V. Kutchin

摘要

Abstract

New functional derivatives of isobornylphenols containing a SCN group at the para-position of the benzene ring were synthesized. It was found that the nature of the solvent influences the reaction course. The use of polar aprotic solvents reduces the reaction time and increases the yield of the target product. The obtained thiocyanate derivatives of isobornylphenols exhibit antioxidant activity in various in vitro models.