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Abstract <p>A series of 3,4,5,6,7,8-hexahydro-4-aryl-8-arylidene-2(1<i>H</i>)-quinazolinethiones was obtained by the reaction of cyclohexanone bis-chalcones with thiourea. Further modification using chloroethynylphosphonate afforded a series of new phosphorylated thiazolo[2,3-<i>b</i>]quinazoline derivatives.</p>

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Synthesis of 3,4,5,6,7,8-Hexahydro-4-aryl-8-arylidene-2(1H)-quinazolinethiones and Their Reactions with Dialkyl Chloroethynylphosphonates

  • 期刊论文

  • 发表日期：

    2026年5月7日

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  • Anastasia S. Skrylkova,
  • Dmitry M. Egorov,
  • Dar’ya V. Spiridonova

摘要

Abstract

A series of 3,4,5,6,7,8-hexahydro-4-aryl-8-arylidene-2(1H)-quinazolinethiones was obtained by the reaction of cyclohexanone bis-chalcones with thiourea. Further modification using chloroethynylphosphonate afforded a series of new phosphorylated thiazolo[2,3-b]quinazoline derivatives.