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Abstract <p>This paper describes the synthesis and investigation of new substituted potassium 3-(thiophen-2-yl)amino-5-oxopenta-1,3-dien-2-olate derivatives which can be used in agriculture and have minimal acute toxicity. The obtained substances were characterized by FTIR spectroscopy, NMR spectroscopy, and elemental analysis. Quantitative evaluation of the cytotoxic effect of the developed compounds was identified, and it was determined the seeds germination rate, morpho- and mass-metric characteristics. The results showed that several synthesized compounds demonstrate a high level of biological activity with a low level of acute toxicity. Thus, this indicates the perspectives of further research on this class of compounds.</p>

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Synthesis of Substituted Potassium 3-(Thiophen-2-yl)amino-5-oxopenta-1,3-dien-2-olate Derivatives as New Low-Toxicity Sources of Potassium for Agricultural Crops

  • 期刊论文

  • 发表日期：

    2025年12月1日

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  • Natalya A. Nosova,
  • Irina A. Gorbunova,
  • Anna S. Zhuravleva,
  • Nailia R. Iamalova,
  • Gayane G. Panova,
  • Ramiz R. Makhmudov,
  • Vladislava A. Rusakova,
  • Alexander S. Timin,
  • Anastasiya V. Penkova,
  • Sergei A. Shipilovskikh

摘要

Abstract

This paper describes the synthesis and investigation of new substituted potassium 3-(thiophen-2-yl)amino-5-oxopenta-1,3-dien-2-olate derivatives which can be used in agriculture and have minimal acute toxicity. The obtained substances were characterized by FTIR spectroscopy, NMR spectroscopy, and elemental analysis. Quantitative evaluation of the cytotoxic effect of the developed compounds was identified, and it was determined the seeds germination rate, morpho- and mass-metric characteristics. The results showed that several synthesized compounds demonstrate a high level of biological activity with a low level of acute toxicity. Thus, this indicates the perspectives of further research on this class of compounds.