Abstract <p>This study reports the plant-mediated synthesis of silver nanoparticles (AgNPs) using <i>Syzygium stocksii</i> (Duthie) leaf extract as a natural reducing and stabilizing agent. The synthesized AgNPs were characterized using UV-visible spectroscopy, Fourier-transform infrared spectroscopy (FTIR), powder X-ray diffraction (PXRD), scanning electron microscopy (SEM), energy-dispersive X-ray analysis (EDX), and thermogravimetric analysis (TGA). The SPR peak observed at 427 nm and a band gap energy of 2.93 eV confirmed the formation of AgNPs. PXRD analysis revealed crystalline AgNPs with an average crystallite size of 28–35 nm and a face-centered cubic structure (JCPDS No. 04-0783), with no peaks corresponding to silver oxide or silver nitrate. FTIR and TGA data indicated the absence of significant organic residues or nitrate species post-synthesis. SEM-EDX analysis confirmed spherical morphology and high elemental purity (~98.69% Ag). Biological evaluation revealed that AgNPs exhibited moderate antioxidant activity (24.69% DPPH inhibition at 1000 µg/mL) and promising anti-inflammatory effects (20.26% inhibition in the hemolysis model at 300 µg/mL). The findings suggest that <i>S. stocksii</i>-mediated AgNPs have potential biomedical applications and highlight the benefits of eco-conscious nanoparticle synthesis.</p>

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Eco-Friendly Fabrication of Silver Nanoparticles Using Syzygium stocksii Leaf Extract: Physicochemical Characterization and Evaluation of Antioxidant and Anti-Inflammatory Activities

  • H. N. Akolkar,
  • G. B. Pawar,
  • D. N. Raut,
  • G. K. Prashanth,
  • H. S. Lalithamba,
  • S. Rao,
  • N. R. Darekar

摘要

Abstract

This study reports the plant-mediated synthesis of silver nanoparticles (AgNPs) using Syzygium stocksii (Duthie) leaf extract as a natural reducing and stabilizing agent. The synthesized AgNPs were characterized using UV-visible spectroscopy, Fourier-transform infrared spectroscopy (FTIR), powder X-ray diffraction (PXRD), scanning electron microscopy (SEM), energy-dispersive X-ray analysis (EDX), and thermogravimetric analysis (TGA). The SPR peak observed at 427 nm and a band gap energy of 2.93 eV confirmed the formation of AgNPs. PXRD analysis revealed crystalline AgNPs with an average crystallite size of 28–35 nm and a face-centered cubic structure (JCPDS No. 04-0783), with no peaks corresponding to silver oxide or silver nitrate. FTIR and TGA data indicated the absence of significant organic residues or nitrate species post-synthesis. SEM-EDX analysis confirmed spherical morphology and high elemental purity (~98.69% Ag). Biological evaluation revealed that AgNPs exhibited moderate antioxidant activity (24.69% DPPH inhibition at 1000 µg/mL) and promising anti-inflammatory effects (20.26% inhibition in the hemolysis model at 300 µg/mL). The findings suggest that S. stocksii-mediated AgNPs have potential biomedical applications and highlight the benefits of eco-conscious nanoparticle synthesis.