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Abstract <p>Based on 3-chloro-6-hydrazinylpyridazine, a series of new derivatives containing the arylidenehydrazinyl-6-chloropyridazine fragment, were synthesized using conventional methods and under microwave irradiation. Experimental data indicate that when using a technique that meets the requirements of green chemistry, in the vast majority of cases higher yields of final products are achieved with a simultaneous sharp reduction in reaction times, which leads to significant savings in energy resources. Biological tests were carried out on seeds and seedlings of common bean (<i>Phaseolus vulgaris L</i>.). The screening showed that the synthesized compounds exhibit pronounced stimulating activity in plant growth and may be promising in searching for new growth stimulators. In silico study of synthesized compounds were carried out.</p>

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Microwave-Assisted Green Synthesis, In Silico Study, and Plant Growth Stimulant Activity of Novel 3-(2-Arylidenehydrazinyl)-6-chloropyridazines

  • 期刊论文

  • 发表日期：

    2025年3月27日

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  • E. A. Ghazaryan,
  • T. A. Gomktsyan,
  • A. V. Karapetyan,
  • Y. A. Gharibyan,
  • T. K. Gharibyan,
  • S. V. Harutyunyan,
  • M. V. Dovlatyan,
  • S. A. Hunanyan,
  • A. O. Markosian,
  • A. P. Yengoyan,
  • A. S. Vorskanyan

摘要

Abstract

Based on 3-chloro-6-hydrazinylpyridazine, a series of new derivatives containing the arylidenehydrazinyl-6-chloropyridazine fragment, were synthesized using conventional methods and under microwave irradiation. Experimental data indicate that when using a technique that meets the requirements of green chemistry, in the vast majority of cases higher yields of final products are achieved with a simultaneous sharp reduction in reaction times, which leads to significant savings in energy resources. Biological tests were carried out on seeds and seedlings of common bean (Phaseolus vulgaris L.). The screening showed that the synthesized compounds exhibit pronounced stimulating activity in plant growth and may be promising in searching for new growth stimulators. In silico study of synthesized compounds were carried out.