Phosphine-Catalyzed α-Umpolung and Vicinal Bis-Addition of Imides and Hydantoins to Methyl Propiolate
摘要
Abstract
A series of α-imido- or -hydantoinoacrylates was obtained. The antimicrobial activity of these compounds against gram-positive and gram-negative bacteria and fungi was studied. In addition, data were obtained on the synthesis of 2,3-bisimido- or -bishydantoinopropanoates containing both identical heterocyclic fragments and different ones with α- and β-carbon atoms in one molecule.