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Performic Acid–Sulfuric Acid System as a Key Reagent for the Synthesis of Allobetulone A-seco-derivatives

  • M. P. Yakovleva,
  • V. A. Vydrina,
  • R. R. Sayakhov,
  • G. Yu. Ishmuratov

摘要

Abstract

The performic acid–sulfuric acid system in methylene chloride was proposed as a key reagent for the synthesis of a number of A-seco-derivatives of allobetulone. As a result, from the same substrate (allobetulone) and reagent (formic acid in methylene chloride), depending on different amounts and method of adding sulfuric acid, 4 differently functionalized derivatives of allobetulon (unsaturated acid, keto acid, formyloxy acid and diacid) were obtained.