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Study of 2-Amino-4-aroyl-6-halopyridine-3,5-dicarbonitriles as Reagents for Quantitative Determination of Mercury(II) Ions

  • E. N. Ramskaya,
  • Ya. S. Kayukov,
  • O. V. Kayukova,
  • A. N. Lyshchikov,
  • A. U. Alekseeva,
  • I. N. Bardasov

摘要

Abstract

A new approach to the synthesis of 2-amino-4-aroyl-6-halopyridine-3,5-dicarbonitriles using commercially available saturated solutions of hydrogen halides is proposed. The synthesized compounds demonstrated binding properties towards mercury(II) ions, which is manifested in fluorescence quenching. The limit of mercury(II) detection with a leading compound falls in the nanomolar range, which is comparable to the known reagents based on small molecule compounds.