Regioselective Oxidation of 6-Hydroxymethylpyridoxine Derivatives of Pyridoxine

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发表日期：

2024年7月1日

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R. M. Khaziev,
N. V. Shtyrlin,
R. M. Vafina,
D. R. Islamov,
E. I. Romanova,
Y. G. Shtyrlin

摘要

Abstract

An approach to the stereoselective oxidation of 5,6-bis(hydroxymethyl)-2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridine and 5,6-bis(hydroxymethyl)-2,4-dimethyl-3-hydroxypyridine with manganese dioxide has been developed, intermediates and by-products have been isolated. In solutions, pyridoxine derivatives containing a carbaldehyde group exist in cyclic hemiacetal and open hydroxyaldehyde forms.