Synthesis of Novel Spirochromanone/1,2,3-Triazole Hybrid Heterocycles as Potential Antimicrobial Agents

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发表日期：

2024年6月1日

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M. Raju,
Y. Hemasri,
Y. Jayaprakash Rao

摘要

Abstract

A series of new hybrid spirochromanone-1,2,3-triazole derivatives have been synthesized by employing a Cu(I)-catalyzed azide-alkyne [3+2] cycloaddition reaction. All compounds were characterized using ¹H NMR, ¹³C NMR and HRMS methods. In addition, all synthesized compounds were tested in vitro for antimicrobial activity.