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Cyanothioacetamide in Multicomponent Synthesis of 2-Thionicotinonitrile Derivatives

  • I. V. Dyachenko,
  • V. D. Dyachenko,
  • P. V. Dorovatovskiy,
  • V. N. Khrustalev,
  • V. G. Nenaidenko

摘要

Abstract

Multicomponent condensation of cyanothioacetamide, carbonyl compounds, enamines and alkylating reagents initiated by the Knoevenagel reaction led to the formation of 2-thionicotinonitriles. The molecular and crystal structure of the prepared products was studied by single crystal X-ray diffraction method.