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3-Aminofuro[2,3-b]pyridines: Reaction with N-Chlorosuccinimide and Sodium Hypochlorite

  • T. A. Stroganova,
  • V. K. Vasilin,
  • N. V. Shitikov,
  • I. G. Dmitrieva,
  • G. D. Krapivin

摘要

Abstract

The reaction of aminoamides of the furo[2,3-b]pyridine series with an aqueous solution of sodium hypochlorite and N-chlorosuccinimide was studied. It was found that the chlorination reaction proceeds at position 2 of the furopyridine system, leading to previously unknown 3-imino-2-chlorofuro[2,3-b]pyridine-2-carboxamides. For some synthesized compounds, nucleophilic substitution reactions were investigated. Among the obtained substances, compounds were identified that have antidote activity against 2,4-D.