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Peculiarities of the Knott Aryliminomethylation Reaction of 7-Hydroxy-4-methylcoumarin: Formation of the 6-Substituted Regioisomer

  • N. L. Zaichenko,
  • A. V. Liubimov,
  • G. V. Liubimova,
  • L. S. Koltsova,
  • I. R. Mardaleishvili,
  • A. I. Shienok

摘要

Abstract

One-pot synthesis of azomethinocoumarins by the Knott reaction of 4-methyl-7-hydroxycoumarin with ethyl orthoformate and arylamines afforded 8-substituted product along with minor 6-substituted regioisomers in some cases.