Features of the Reaction of (1,2-Dibromoethyl)(diphenyl)phosphine Oxide with CH- and NH-Nucleophiles

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发表日期：

2024年1月1日

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G. Ts. Gasparyan,
A. S. Bichakhchyan,
L. V. Derdzyan,
S. Kh. Avetisyan,
H. A. Panosyan,
А. S. Pogosyan

摘要

Abstract

The reaction of (1,2-dibromoethyl)(diphenyl)phosphine oxide with CH-acids (acetylacetone, acetoacetic ester, and malonic ester) in the presence of sodium hydroxide has afforded diphenylphosphoryl-substituted cyclopropanes in high yield. It has been shown that the reaction of (1,2-dibromoethyl)(diphenyl)phosphine oxide with primary arylamines leads to the formation of bis(phosphine oxides), in contrast to alkylamines which lead to phosphoryl-substituted aziridines.