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Synthesis of a New Cobalt Complex with Catechol Dianion and Study of the Kinetics of Its Redox-Activated Dissociation

  • E. A. Khakina,
  • I. A. Nikovskii,
  • A. A. Danshina,
  • E. P. Antoshkina,
  • A. N. Rodionov,
  • Yu. V. Nelyubina

摘要

Abstract

A new redox-active cobalt(III) complex with a catechol dianion and two 4,4'-dimethoxy-2,2'-bipyridine ligands was synthesized. The reduction of the complex with ascorbic acid in an inert atmosphere was studied by NMR spectroscopy in situ. The reaction followed the first-order kinetics with respect to the starting complex, had a rate constant of 1.1 × 10–3 s–1, and was accompanied by the release of catechol, which served as a model drug.