Flowsheet Testing for Separation of Lutetium-177 from an Irradiated Ytterbium Target
摘要
Abstract
The results of an experiment to verify a complex technology for isolation of 177Lu from an irradiated 1-g ytterbium target are presented. The main components of the experimental installation, which is mounted in a research hot cell, are described. These components include the extraction and separation of lutetium and ytterbium, the evaporation and preconcentration of 177Lu, and its chromatographic purification. The feasibility of obtaining a pharmaceutical substance no carrier added lutetium-177 trichloride that meets the standards set by the European Pharmacopoeia has been confirmed.