Preparation of Tritium Labeled Dexamethasone Phosphate and Its Application to Assess the Affinity of Ligands for Glucocorticoid Receptors

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发表日期：

2024年8月1日

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G. A. Badun,
E. M. Zhidkova,
M. G. Chernysheva,
A. D. Enikeev,
M. G. Yakubovskaya,
E. A. Lesovaya

摘要

Abstract

The possibility of introducing tritium into dexamethasone and dexamethasone phosphate using the thermal activation method was demonstrated. The affinity of ligands for glucocorticoid receptors has been successfully assessed using labeled compounds.