Abstract <p>Magnetic nanoparticle-polymer nanocomposites have been well encouraged as magnetic resonance imaging (MRI) contrast agents with high performance. The advanced nanocomposites combine with magnetic contours such as superparamagnetism and high relaxivity, which are limited to nanoparticles with the structural and functional flexibility of polymers. Additionally, it improves the particular functionalisation, biocompatibility, and structure of imaging contrast agents, which raises the diagnostic yield. This paper discusses the various manufacturing processes for magnetic nanoparticle-polymer nanocomposites, their structure, and how they enhance MRI contrast. Their ability to improve diagnostics, reduce the required dosage, and allow real-time imaging makes these nanocomposites potent tools for the development of new medical imaging technologies. We also discuss future prospects and concerns with regard to the further advancement of these materials for clinic use.</p>

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Magnetic Nanoparticle-Polymer Nanocomposites for Enhanced Magnetic Resonance Imaging (MRI) Contrast Agents: A Review

  • Vinoth Kuzha,
  • K. Radhakrishnan,
  • A. Dinesh,
  • Kurinjinathan Panneerselvam,
  • Lalitha Gnanasekaran,
  • V. Mohanavel,
  • E. Priyadharshini,
  • Manikandan Ayyar,
  • Ratnesh Tiwari,
  • Madhappan Santhamoorthy,
  • Saravana Kumar Jaganathan

摘要

Abstract

Magnetic nanoparticle-polymer nanocomposites have been well encouraged as magnetic resonance imaging (MRI) contrast agents with high performance. The advanced nanocomposites combine with magnetic contours such as superparamagnetism and high relaxivity, which are limited to nanoparticles with the structural and functional flexibility of polymers. Additionally, it improves the particular functionalisation, biocompatibility, and structure of imaging contrast agents, which raises the diagnostic yield. This paper discusses the various manufacturing processes for magnetic nanoparticle-polymer nanocomposites, their structure, and how they enhance MRI contrast. Their ability to improve diagnostics, reduce the required dosage, and allow real-time imaging makes these nanocomposites potent tools for the development of new medical imaging technologies. We also discuss future prospects and concerns with regard to the further advancement of these materials for clinic use.