Scholarlink

Abstract <p>We propose a method of Fisher information calculation for super-resolution optical fluctuation imaging (SOFI) with a realistic multiparametric model, taking into account finite acquisition time and non-trivial emitters’ blinking induced signal correlations. Computational efficiency is ensured by separation of geometrical effects from statistical description of emitters’ blinking and shot noise. Fisher information matrices were successfully constructed for SOFI images up to the 4th order and used for spatial resolution quantification.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Construction of Fisher Information Matrix for Multiparametric Problem in Super-Resolution Optical Fluctuation Imaging

  • 期刊论文

  • 发表日期：

    2025年10月25日

查看全文
  • A. B. Mikhalychev,
  • D. A. Lyakhov,
  • S. V. Mikhalycheva,
  • S. Ya. Kilin

摘要

Abstract

We propose a method of Fisher information calculation for super-resolution optical fluctuation imaging (SOFI) with a realistic multiparametric model, taking into account finite acquisition time and non-trivial emitters’ blinking induced signal correlations. Computational efficiency is ensured by separation of geometrical effects from statistical description of emitters’ blinking and shot noise. Fisher information matrices were successfully constructed for SOFI images up to the 4th order and used for spatial resolution quantification.