Using Time-Resolved Microscopy to Investigate Subcellular Hyperthermia
摘要
Abstract
The authors investigate patterns of the laser heating of iron oxide nanoparticles depending on their size, shape, and aggregation at the subcellular level. Temperature is measured via time-resolved fluorescence thermometry based on rhodamine B dye. Estimated temperatures are over 100°C, creating favorable conditions for the programmed cell death of tumor cells upon laser hyperthermia.