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Microfluidic-Assisted Synthesis of Hybrid Carbonate Calcium Microparticles Modified by Silver Nanoparticles

  • A. V. Ermakov,
  • S. V. Chapek,
  • E. V. Lengert,
  • P. V. Konarev,
  • V. V. Volkov,
  • M. A. Soldatov,
  • D. B. Trushina

摘要

Abstract

The development of advanced methods for the synthesis of nano- and microparticles for biomedical applications is of considerable interest. A method for synthesizing submicron silver-shelled calcium carbonate particles using a microfluidic chip designed to control the particle formation is proposed. Precise control of reaction parameters enables controlled formation of silver shell and calcium carbonate particles. The distribution of pores in the hybrid particles was analyzed using small-angle X-ray scattering, which gained insight into the complex structure of the pores. The results provide information on the particle morphology and may facilitate the development of new calcium carbonate-based materials for various applications.