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Abstract <p>A method for immobilizing DNA aptamers on the surface of a porous polyethylene terephthalate substrate and gold nanoparticles has been developed, preserving the functionality of the recognition elements. The possibility of assembling a ternary complex composed of aptamer-functionalized porous polymeric substrate, influenza A virus, and aptamer-functionalized gold nanoparticles is shown. These results can be used to create aptamer-based test strips.</p>

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Influenza A Virus Determination Using an Aptamer-Based Colorimetric Test System

  • 期刊论文

  • 发表日期：

    2026年2月1日

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  • D. S. Tikhonova,
  • E. V. Andreev,
  • T. S. Grishin,
  • S. V. Dubkov,
  • A. N. Nechaev,
  • P. Yu. Apel,
  • E. G. Zavyalova

摘要

Abstract

A method for immobilizing DNA aptamers on the surface of a porous polyethylene terephthalate substrate and gold nanoparticles has been developed, preserving the functionality of the recognition elements. The possibility of assembling a ternary complex composed of aptamer-functionalized porous polymeric substrate, influenza A virus, and aptamer-functionalized gold nanoparticles is shown. These results can be used to create aptamer-based test strips.