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Abstract <p>The effect of a bifido- and lactobacilli complex on some indices of nonspecific humoral immunity of the sturgeon hybrid <i>Acipenser gueldaenstaedti</i> Brandt × <i>A. baeri</i> Brandt has been studied. The level of antimicrobial properties, C-reactive protein, and lysozyme and the content of nonspecific immune complexes in serum were studied. This study showed a high level of bacteriostatic activity and lysozyme, a low content of nonspecific immune complexes in the experimental groups compared to the control, which indicates the immunostimulating effect of the bifidobacteria and lactobacilli complex on nonspecific mechanisms of the antibacterial defense of fish.</p>

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Immunomodulatory Effect of a Bifido- and Lactobacilli Complex on Nonspecific Humoral Immunity of Sturgeon Fish Hybrids

  • 期刊论文

  • 发表日期：

    2025年4月1日

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  • A. D. Zhandalgarova,
  • D. V. Mikryakov,
  • Yu. N. Grozesku,
  • A. A. Bakhareva,
  • T. A. Suvorova,
  • T. A. Subbotkina,
  • M. F. Subbotkin,
  • S. V. Kuzmicheva

摘要

Abstract

The effect of a bifido- and lactobacilli complex on some indices of nonspecific humoral immunity of the sturgeon hybrid Acipenser gueldaenstaedti Brandt × A. baeri Brandt has been studied. The level of antimicrobial properties, C-reactive protein, and lysozyme and the content of nonspecific immune complexes in serum were studied. This study showed a high level of bacteriostatic activity and lysozyme, a low content of nonspecific immune complexes in the experimental groups compared to the control, which indicates the immunostimulating effect of the bifidobacteria and lactobacilli complex on nonspecific mechanisms of the antibacterial defense of fish.