Scholarlink

Abstract <p>The objective of this investigation is to develop optimization approaches for the separation of platelets from red blood cells (<b>RBC</b>s). A novel microfluidic device with triangular electrodes operating at a low voltage of 1.5 V and a frequency of 100 kHz is proposed for the separation of platelets and RBCs using dielectrophoresis (<b>DEP</b>) force. Using of a low voltage ensures the preservation of the viability of biological cells, which is a crucial factor for medical applications. Through a comparative investigation utilizing the finite element method, the impact of varying electrode dimensions on the effective separation of particles is demonstrated. Profiles of electric field, pressure, and DEP force acting on two particles are presented through simulation.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Simulation and Optimization of a Low-Voltage Microseparator Based on Dielectrophoresis Forces for Blood Cell Separation

  • 期刊论文

  • 发表日期：

    2025年5月1日

查看全文
  • Elnaz Poorreza,
  • Noushin Dadashzadeh Gargari

摘要

Abstract

The objective of this investigation is to develop optimization approaches for the separation of platelets from red blood cells (RBCs). A novel microfluidic device with triangular electrodes operating at a low voltage of 1.5 V and a frequency of 100 kHz is proposed for the separation of platelets and RBCs using dielectrophoresis (DEP) force. Using of a low voltage ensures the preservation of the viability of biological cells, which is a crucial factor for medical applications. Through a comparative investigation utilizing the finite element method, the impact of varying electrode dimensions on the effective separation of particles is demonstrated. Profiles of electric field, pressure, and DEP force acting on two particles are presented through simulation.