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Abstract <p>Genetic testing of animals is currently an essential part of the development of the agro-industrial complex. The unique characteristics of indigenous cow breeds are an important genetic resource in the dairy farming, essential for improving commercially valuable traits and meeting growing consumer demand for high-quality, ecofriendly dairy products. This article presents our own developments for cattle genotyping using TaqMan technology. As the result of genetic association studies, it was found that, in order to increase milk yield on average over 305 days of lactation for the Tagil breed, negative selection for the <i>G*</i> allele is recommended for rs110347054, while positive selection for the <i>T*</i> allele is recommended for rs41567027. For the Istobenskaya breed, positive selection for the <i>C*</i> allele is recommended for rs109529386. It is noted that the limitations of this study for association tests are unique for selection of native breeds and their sample size because of their endangered status. The aim of this work is to study the features of the milk productivity phenotype and genetic associations of 13 SNPs for the main parameters of milk productivity for five cattle breeds.</p>

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Inheritance Patterns of Dairy Productivity Traits in Cattle: The Contribution of SNPs and Their Epistasis

  • 期刊论文

  • 发表日期：

    2026年3月16日

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  • O. S. Zaitseva,
  • V. V. Kozhukhovskaya,
  • O. Yu. Oparina,
  • M. V. Bytov,
  • V. D. Zubareva

摘要

Abstract

Genetic testing of animals is currently an essential part of the development of the agro-industrial complex. The unique characteristics of indigenous cow breeds are an important genetic resource in the dairy farming, essential for improving commercially valuable traits and meeting growing consumer demand for high-quality, ecofriendly dairy products. This article presents our own developments for cattle genotyping using TaqMan technology. As the result of genetic association studies, it was found that, in order to increase milk yield on average over 305 days of lactation for the Tagil breed, negative selection for the G* allele is recommended for rs110347054, while positive selection for the T* allele is recommended for rs41567027. For the Istobenskaya breed, positive selection for the C* allele is recommended for rs109529386. It is noted that the limitations of this study for association tests are unique for selection of native breeds and their sample size because of their endangered status. The aim of this work is to study the features of the milk productivity phenotype and genetic associations of 13 SNPs for the main parameters of milk productivity for five cattle breeds.