Comparative Analysis of Mutation in the Buccal Epithelium and Blood in Patients with Lung Cancer and Healthy People

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发表日期：

2024年5月21日

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O. V. Serzhantova,
A. G. Novikova,
A. A. Mikhailov,
I. P. Moshurov,
A. P. Gureev

摘要

Abstract

Lung cancer is one of the leading causes of cancer death. Finding new methods for the early and accurate diagnosis of lung cancer is critical for effective treatment. We have shown that patients with lung cancer in the buccal epithelium have more mutations in the FLT3, PDGFRA, KDR, PIK3CA, HRAS, and FGFR3 genes than people without diagnosed lung cancer. Thus, study of molecular changes may be used as a method for the accurate diagnosis of lung cancer at early stages of investigation.