Abstract <p>We address a possible development of a semiotic theory based on the principle of asymmetric dualism proposed by Sergei Karcevskij. We identify its differences from the Saussurean view of sign and demonstrate that, while Karcevskij adopts the principle of differentiation, he supplements it with a dynamic understanding of intrasystem relations. This makes it possible to construct multidimensional semiotic models describing how new meanings are generated due to the sign’s asymmetric dualism. We consider the semantics of linguistic sign as a structure in the state of dynamic equilibrium. Thus, we clarify Karcevskij’s concept of transposition, supplementing it with a concept of disposition (situation of the initial semiosis).</p>