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Abstract <p>A method for producing tetraalkylammonium bromide with one long aliphatic radical in a polar organic solvent medium is described. Isopropyl alcohol is recommended as the solvent for the alkylation reaction of triethylamine with octadecyl bromide, proceeding via a bimolecular nucleophilic substitution mechanism. The influence of the synthesis temperature of triethyloctadecylammonium bromide in isopropyl alcohol on the yield of the target reaction product was studied.</p>

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Synthesis of Tetraalkylammonium Bromide in an Organic Solvent Medium

  • 期刊论文

  • 发表日期：

    2025年4月1日

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  • K. Shikolenko,
  • A. P. Mikhaylovskaya

摘要

Abstract

A method for producing tetraalkylammonium bromide with one long aliphatic radical in a polar organic solvent medium is described. Isopropyl alcohol is recommended as the solvent for the alkylation reaction of triethylamine with octadecyl bromide, proceeding via a bimolecular nucleophilic substitution mechanism. The influence of the synthesis temperature of triethyloctadecylammonium bromide in isopropyl alcohol on the yield of the target reaction product was studied.