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Abstract <p>In the present work, the copper(II) resistance of <i>Achromobacter insolitus</i> strain LCu2 was decreased by adding 1 µM of silver nanoclusters to the culture medium: the maximum tolerant concentration decreased 4 times and the minimum inhibitory concentration decreased 25 times. It is supposed that nanoclusters disturb the function of the copper(II) efflux system by binding to the CusC protein; as a result, the bacteria partially lose the ability to export excessive copper(II) cations from the cells.</p>

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Effect of Silver Nanoclusters on the Copper Resistance of Achromobacter insolitus LCu2

  • 期刊论文

  • 发表日期：

    2025年4月1日

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  • G. L. Burygin,
  • A. S. Astankova,
  • D. S. Chumakov,
  • E. V. Kryuchkova

摘要

Abstract

In the present work, the copper(II) resistance of Achromobacter insolitus strain LCu2 was decreased by adding 1 µM of silver nanoclusters to the culture medium: the maximum tolerant concentration decreased 4 times and the minimum inhibitory concentration decreased 25 times. It is supposed that nanoclusters disturb the function of the copper(II) efflux system by binding to the CusC protein; as a result, the bacteria partially lose the ability to export excessive copper(II) cations from the cells.