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Abstract <p>Three new aroylhydrazones are prepared by reaction of 4-hydroxy-3-nitrobenzaldehyde with 4-bromobenzohydrazide, 3-trifluoromethylbenzohydrazide and 2-aminobenzohydrazide, respectively in MeOH. The three compounds are characterized by elemental analysis, IR and <sup>1</sup>H NMR spectra. Detailed structures of the compounds are determined by single crystal X-ray diffraction. Antibacterial activities of the compounds are evaluated on <i>E. coli, P. aeruginosa, B. subtilis, and S. aureus</i> and show high potency.</p>

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Synthesis, Characterization and Crystal Structures of Aroylhydrazones Derived from 4-Hydroxy-3-Nitrobenzaldehyde with Various Hydrazides

  • 期刊论文

  • 发表日期：

    2026年4月1日

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  • Y. Wang,
  • W. Li,
  • N. Song

摘要

Abstract

Three new aroylhydrazones are prepared by reaction of 4-hydroxy-3-nitrobenzaldehyde with 4-bromobenzohydrazide, 3-trifluoromethylbenzohydrazide and 2-aminobenzohydrazide, respectively in MeOH. The three compounds are characterized by elemental analysis, IR and 1H NMR spectra. Detailed structures of the compounds are determined by single crystal X-ray diffraction. Antibacterial activities of the compounds are evaluated on E. coli, P. aeruginosa, B. subtilis, and S. aureus and show high potency.