Scholarlink

Abstract <p>This work compared the effect of different periods of rathousing in crowded conditions on their spatial learning in the Morriswater maze. Experiments were carried out on 65 adult male Wistarrats. In crowded conditions (18 individuals per standard cage),the rats were kept starting from 3 months of age until the end ofthe experiments, while control rats were housed in standard conditions (5&#xa0;individualsper cage). Training in the Morris water maze was conducted at 4,8, and 20 months of age, focusing on the manifestations of bothlong-term and working memory. Young (4-month-old) rats kept in crowdedconditions learned to find the hidden underwater platform betterthan control rats, as manifested in a shorter distance swum to theplatform. In middle and old age, crowded and standard rats did notdiffer in spatial learning. Learning with working memory deterioratedin old age regardless of housing conditions. The swimming speedin rats kept in crowded conditions was lower in all age groups.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

The Effect of Different Crowding Duration and Age on Spatial Learning in Rats in the Morris Water Maze

  • 期刊论文

  • 发表日期：

    2026年2月26日

查看全文
  • M. I. Zaichenko,
  • A. A. Potekhina,
  • E. V. Loseva

摘要

Abstract

This work compared the effect of different periods of rathousing in crowded conditions on their spatial learning in the Morriswater maze. Experiments were carried out on 65 adult male Wistarrats. In crowded conditions (18 individuals per standard cage),the rats were kept starting from 3 months of age until the end ofthe experiments, while control rats were housed in standard conditions (5 individualsper cage). Training in the Morris water maze was conducted at 4,8, and 20 months of age, focusing on the manifestations of bothlong-term and working memory. Young (4-month-old) rats kept in crowdedconditions learned to find the hidden underwater platform betterthan control rats, as manifested in a shorter distance swum to theplatform. In middle and old age, crowded and standard rats did notdiffer in spatial learning. Learning with working memory deterioratedin old age regardless of housing conditions. The swimming speedin rats kept in crowded conditions was lower in all age groups.