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Immunofluorescent Localization of Ca2+ Sensor Proteins in Somatic Motor Muscles of the Earthworm Lumbricus terrestris

  • L. F. Nurullin,
  • N. D. Almazov,
  • E. M. Volkov

摘要

Abstract

Immunofluorescent labeling revealed calmodulin, Ca2+/calmodulin-dependentprotein kinases I and II, synaptotagmin II and VII, and calcineurinA in somatic motor muscles of the earthworm Lumbricus terrestris.These Ca2+ sensor proteins are detectedin both synaptic and extrasynaptic regions. However, synaptotagminII and VII, as well as calcineurin A, are mainly localized in thearea of neuromuscular junctions, with the synaptic localizationfor synaptotagmin VII and calcineurin A being pronounced most distinctly.