<p>The morphology and phase composition of a concentration series of HfO<sub>2</sub>–<InlineEquation ID="IEq1"> <EquationSource Format="TEX">\(x\)</EquationSource> <!--JETPLet2560940Polina-m1--> </InlineEquation> mol % Yb<sub>2</sub>O<sub>3</sub> (<i>x</i> = 0, 5, 10, 15, 30) nanoparticles, obtained by a coprecipitation method, have been studied. The characteristics of thermal radiation, arising in ZrO<sub>2</sub>–30 mol % Yb<sub>2</sub>O<sub>3</sub> and HfO<sub>2</sub>–30 mol % Yb<sub>2</sub>O<sub>3</sub> nanoparticles exposed to laser radiation with the wavelength <InlineEquation ID="IEq2"> <EquationSource Format="TEX">\({{\lambda }_{{{\text{exc}}}}} = 980{\kern 1pt} \)</EquationSource> <!--JETPLet2560940Polina-m2--> </InlineEquation> nm and a high power density, have been comparatively analyzed. The cytotoxicity of HfO<sub>2</sub>–<InlineEquation ID="IEq3"> <EquationSource Format="TEX">\(x\)</EquationSource> <!--JETPLet2560940Polina-m3--> </InlineEquation> mol % Yb<sub>2</sub>O<sub>3</sub> (<InlineEquation ID="IEq4"> <EquationSource Format="TEX">\(x = 15\)</EquationSource> <!--JETPLet2560940Polina-m4--> </InlineEquation>, 30) nanoparticles has been studied. It has been demonstrated that an increase in the content of Yb<sub>2</sub>O<sub>3</sub> in particles from 15 to 30 mol % and the effect of 980-nm laser radiation on them double a cytotoxic effect of these particles relative to the Mh22 cell line.</p>

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Peculiarities of Heating Under Laser Excitation and Cytotoxicity of HfO2–Yb2O3 Nanoparticles

  • P. A. Ryabochkina,
  • A. S. Alekseeva,
  • A. S. Bikeev,
  • O. A. Kulikov,
  • V. I. Shlyapkina,
  • N. Yu. Tabachkova,
  • T. V. Volkova,
  • N. V. Sidorova,
  • V. S. Bobrov,
  • M. V. Gerasimov

摘要

The morphology and phase composition of a concentration series of HfO2 \(x\) mol % Yb2O3 (x = 0, 5, 10, 15, 30) nanoparticles, obtained by a coprecipitation method, have been studied. The characteristics of thermal radiation, arising in ZrO2–30 mol % Yb2O3 and HfO2–30 mol % Yb2O3 nanoparticles exposed to laser radiation with the wavelength \({{\lambda }_{{{\text{exc}}}}} = 980{\kern 1pt} \) nm and a high power density, have been comparatively analyzed. The cytotoxicity of HfO2 \(x\) mol % Yb2O3 ( \(x = 15\) , 30) nanoparticles has been studied. It has been demonstrated that an increase in the content of Yb2O3 in particles from 15 to 30 mol % and the effect of 980-nm laser radiation on them double a cytotoxic effect of these particles relative to the Mh22 cell line.