The anisotropy of the elastic properties of cubic vanadium monoxide with a wide homogeneity region has been studied for the first time. The elastic constants \({{c}_{{11}}}\) , \({{c}_{{12}}}\) , and \({{c}_{{44}}}\) have been estimated as functions of the oxygen content y in the homogeneity region of VO0.75–VO1.25 of disordered cubic vanadium monoxide VOy. The elastic stiffness constants \({{c}_{{ij}}}\) of disordered cubic monoxide VOy decrease with increasing relative oxygen content y. The elastic moduli depend on the crystallographic direction \([hkl]\) . Large changes in the elastic characteristics of VOy depending on the direction \([hkl]\) indicate a strong anisotropy of the elastic properties of disordered cubic vanadium monoxide. According to the ratio of the bulk B and shear G moduli, polycrystalline vanadium monoxide can be considered as a ductile material.
