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Photosensitizing Properties of a Boron Difluoride Beta-Diketonate Derivative

  • A. E. Egorov,
  • A. G. Mirochnik,
  • E. V. Fedorenko,
  • N. A. Lyubykh,
  • A. A. Kostyukov,
  • A. A. Markova,
  • I. D. Burtsev,
  • M. T. Nguyen,
  • V. I. Pogonin,
  • E. A. Zevakin,
  • V. A. Kuzmin

摘要

Abstract

The photosensitizing ability of a boron difluoride beta-diketonate derivative has been studied. The spectral and luminescent properties of the dye and the spectral-kinetic characteristics of its triplet state have been established. The quantum efficiency of singlet oxygen formation has been determined. The in vitro photosensitizing activity of the dye against tumor cells of colon adenocarcinoma was demonstrated, and the values of dark and photoinduced cytotoxicity were obtained.