Abstract <p>Widespread granites in the Wuzhuerhada area within the Tataleng granitic batholith in NW China show notable U, F, W, B, Rb, Be, and Sn geochemical anomalies. However, the petrogenesis and mineralization potential for them are unexamined for now. This study investigated the major and trace element compositions, zircon U–Pb ages, and zircon Hf isotope and trace element compositions for the Wuzhuerhada rapakivi granite and the granite dyke in it. Two samples for the rapakivi granite yielded weighted mean ²⁰⁶Pb/²³⁸U zircon ages of 430 ± 2 and 433 ± 4 Ma, respectively, and one sample for the granite dyke yielded a weighted mean ²⁰⁶Pb/²³⁸U zircon age of 433 ± 4 Ma, indicating comparable emplacement ages of the Early Silurian granites. Geochemically, the Wuzhuerhada rapakivi granite and the granite dyke are slightly peraluminous, with relatively high ASI values, high alkali contents, and negative Eu anomalies, suggesting I-type granites. Geochemistry and zircon ε_Hf(t) values of –14.2 to –4.9 for them suggest that they were all derived from the partial melting of igneous rocks within the Paleoproterozoic relatively shallow mafic reworked lower crust in a typical syn-collisional setting. Minus ΔFMQ value, low quantitative oxygen fugacity (<i>f</i>O₂), and low Ce⁴⁺/Ce³⁺ ratios for zircons suggest that the studied granites have relatively reduced redox states. But the granite dyke shows fractionated whole-rock geochemistry and contains some hydrothermal-affected zircons, indicating that the granite dyke has more Sn–W–(U) mineralization potential than the rapakivi granite or other neighbour granites. Our contributions would help delineate possible Sn–W–(U) ore-prospecting areas where fractionated granite was emplaced in the South Qilian belt.</p>