Abstract <p>A number of physicochemical characteristics of gold and silver present in the active anticancer drugs Aurumacryl and Argacryl have been investigated. Gold and silver nanoparticles in these preparations were visualized under a microscope and several physicochemical parameters of the nanoparticles, such as the average diameter and zeta potential, were characterized. The concentration of nanoparticles in a liquid medium was also determined. The mechanism for the formation of metallic silver nanoparticles in Argacryl was studied using spectrophotometric and electron paramagnetic resonance techniques on Argacryl samples in the form of films and powder.</p>

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The Characteristics of Gold and Silver Nanoparticles in the Antitumor Drugs Aurumacryl and Argacryl

  • L. A. Ostrovskaya,
  • E. D. Nikolskaya,
  • D. B. Korman,
  • M. B. Sokol,
  • M. A. Klimenko,
  • K. A. Abzaeva,
  • N. V. Bluhterova,
  • I. G. Plashchina,
  • L. A. Wasserman,
  • V. I. Popenko

摘要

Abstract

A number of physicochemical characteristics of gold and silver present in the active anticancer drugs Aurumacryl and Argacryl have been investigated. Gold and silver nanoparticles in these preparations were visualized under a microscope and several physicochemical parameters of the nanoparticles, such as the average diameter and zeta potential, were characterized. The concentration of nanoparticles in a liquid medium was also determined. The mechanism for the formation of metallic silver nanoparticles in Argacryl was studied using spectrophotometric and electron paramagnetic resonance techniques on Argacryl samples in the form of films and powder.