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Abstract <p>The EPR method revealed that as a result of sublingual administration of dinitrosyl iron complexes with the ligand <i>N</i>-acetyl-L-cysteine in rats the transfer and accumulation of stable forms of nitric oxide (NO) occurs in brain tissue. The magnitude of this effect was found to be similar to that observed in the heart, lungs, and liver of the animals.</p>

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Accumulation of Nitric Oxide Stabilized Forms in Rat Organs as a Result of Dinitrosyl Iron Complexes with N-Acetyl-L-Cysteine Ligand Administration

  • 期刊论文

  • 发表日期：

    2025年12月1日

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  • A. A. Timoshin,
  • V. L. Lakomkin,
  • A. A. Abramov,
  • M. V. Ivanova,
  • K. B. Shumaev

摘要

Abstract

The EPR method revealed that as a result of sublingual administration of dinitrosyl iron complexes with the ligand N-acetyl-L-cysteine in rats the transfer and accumulation of stable forms of nitric oxide (NO) occurs in brain tissue. The magnitude of this effect was found to be similar to that observed in the heart, lungs, and liver of the animals.