Scholarlink

Abstract <p>Secondary metabolites, some of which have antimicrobial activity, are a key tool that helps filamentous fungi to occupy a wide variety of ecological niches. In particular, some of these microorganisms are capable of growing on painting materials, which leads to their deterioration. However, this natural reservoir has not been screened for antimicrobial compounds. In the current work, we studied the activity of fungi-destructors of tempera painting isolated in the State Tretyakov Gallery from: the Orthodox icon “Prophet Solomon” of the 18th century—<i>Penicillium chrysogenum</i> STG-117; the Old Russian icon of Sergiev Posadsky school dating to the 15th century—<i>Penicillium rubens</i> STG-305, <i>Penicillium</i> sp. STG-333, <i>P. chrysogenum</i> STG-344, <i>Aspergillus fumigatus</i> STG-345, <i>Penicillium</i> sp. STG-348; and from the Old Believer icon “Descent into Hell” of the 16th century—<i>Syncephalastrum</i> sp. STG-160, <i>Cladosporium sphaerospermum</i> STG-161. The strain <i>Simplicillium lamellicola</i> STG-96 was isolated in Hall 61 of the State Tretyakov Gallery. Optimization of cultivation conditions was carried out for the three strains, STG-96, STG-117 and STG-344, that demonstrated promising antimicrobial activity against panel of representative test cultures on two nutrient media—Czapek-Dox and #2 Gause, with different pH values, in the range of 5.0–10.0. The highest antimicrobial activity was observed at the second and third week of culturing. The antimicrobial activity was also tested for novel isolates: STG-160, STG-161, STG-305, STG-333, STG-345 and STG-348. Strains from the <i>Aspergillaceae</i> family showed high activity against such representative test cultures as methicillin-resistant <i>Staphylococcus aureus</i> (MRSA), <i>Pseudomonas aeruginosa</i> and <i>Mycobacterium smegmatis</i>. Our work demonstrates that fungi-destructors of tempera painting are promising producers of antimicrobial compounds.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Fungi-Destructors of Painting Materials Isolated in the State Tretyakov Gallery as Novel Promising Producers of Antimicrobial Compounds

  • 期刊论文

  • 发表日期：

    2025年10月1日

查看全文
  • A. A. Ermolyuk,
  • D. A. Avdanina,
  • F. S. Koblov,
  • S. G. Kalinin,
  • B. F. Vasilieva,
  • M. V. Demiankova,
  • O. V. Efremenkova,
  • A. A. Zhgun

摘要

Abstract

Secondary metabolites, some of which have antimicrobial activity, are a key tool that helps filamentous fungi to occupy a wide variety of ecological niches. In particular, some of these microorganisms are capable of growing on painting materials, which leads to their deterioration. However, this natural reservoir has not been screened for antimicrobial compounds. In the current work, we studied the activity of fungi-destructors of tempera painting isolated in the State Tretyakov Gallery from: the Orthodox icon “Prophet Solomon” of the 18th century—Penicillium chrysogenum STG-117; the Old Russian icon of Sergiev Posadsky school dating to the 15th century—Penicillium rubens STG-305, Penicillium sp. STG-333, P. chrysogenum STG-344, Aspergillus fumigatus STG-345, Penicillium sp. STG-348; and from the Old Believer icon “Descent into Hell” of the 16th century—Syncephalastrum sp. STG-160, Cladosporium sphaerospermum STG-161. The strain Simplicillium lamellicola STG-96 was isolated in Hall 61 of the State Tretyakov Gallery. Optimization of cultivation conditions was carried out for the three strains, STG-96, STG-117 and STG-344, that demonstrated promising antimicrobial activity against panel of representative test cultures on two nutrient media—Czapek-Dox and #2 Gause, with different pH values, in the range of 5.0–10.0. The highest antimicrobial activity was observed at the second and third week of culturing. The antimicrobial activity was also tested for novel isolates: STG-160, STG-161, STG-305, STG-333, STG-345 and STG-348. Strains from the Aspergillaceae family showed high activity against such representative test cultures as methicillin-resistant Staphylococcus aureus (MRSA), Pseudomonas aeruginosa and Mycobacterium smegmatis. Our work demonstrates that fungi-destructors of tempera painting are promising producers of antimicrobial compounds.