<p>This paper explores the integration of eastern philosophical practices, particularly Self-Enquiry, into contemporary psychotherapy. It begins by examining various philosophical traditions’ views on the self, contrasting eastern and western perspectives. Self-Enquiry, rooted in Indian Vedantic philosophy, offers a unique pathway to psychological well-being by encouraging individuals to question the nature of the self and transcend egoic identification. The practical application of Self-Enquiry in psychotherapy is discussed alongside similar introspective practices such as Isha Kriya, Vipassana, and Zen meditation. These methods foster cognitive realignment and emotional regulation by addressing cognitive distortions at their root. The paper proposes a preliminary methodological framework that incorporates Self-Enquiry into therapeutic practices, highlighting its potential to support clients’ mental health and spiritual growth. The challenges of cultural adaptation, ethical considerations, and therapist competency are examined, emphasizing the importance of specialized guidance in applying these practices. Ultimately, this integration offers an innovative approach to mental health by promoting philosophical health and holistic well-being.</p>