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<p>The concept of a Learning Health System (LHS) has been widely discussed in academic literature, yet its practical implementation remains a challenge. This paper describes the institutional journey, leadership structure, data governance policies, and technical innovations that together support a scalable and sustainable Research-Oriented LHS. Additionally, we propose an expanded data vision that aligns with interdisciplinary and translational research needs. Supplementary materials provide technical details for those interested in implementing such a model.</p>

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Operationalizing a research-oriented learning healthcare system across covered entities: cross-institutional strategies and innovations

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年12月16日

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  • Timothy R. Huerta,
  • Christopher W. Bartlett,
  • Gabriel Alain,
  • Thomas Bentley,
  • Carol R. Bradford,
  • John FP Bridges,
  • Arnab Chakravarti,
  • Alexander A. Farag,
  • Cynthia A. Gerhardt,
  • Tyler Gorham,
  • Shaun J. Grannis,
  • Yungui Huang,
  • Julie A. Johnson,
  • Nina V. Kraguljac,
  • Lang Li,
  • Qin Ma,
  • Puneet Mathur,
  • Marcy Mays,
  • Ann Scheck McAlearney,
  • Eneida A. Mendonca,
  • Sayoko E. Moroi,
  • Xia Ning,
  • Colin Odden,
  • Lauren Phelps,
  • William E. Smoyer,
  • Robert Strouse,
  • Curtis Walker,
  • Ping Zhang,
  • Dukagjin M. Blakaj

摘要

The concept of a Learning Health System (LHS) has been widely discussed in academic literature, yet its practical implementation remains a challenge. This paper describes the institutional journey, leadership structure, data governance policies, and technical innovations that together support a scalable and sustainable Research-Oriented LHS. Additionally, we propose an expanded data vision that aligns with interdisciplinary and translational research needs. Supplementary materials provide technical details for those interested in implementing such a model.