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<p>Cowpea is a vital grain legume in sub-Saharan Africa, providing affordable protein, essential micronutrients, and resilience in marginal environments. However, its genetic improvement is constrained by a narrow genetic base and limited introgression from wild relatives. Tissue culture remains a major bottleneck for deploying gene editing, due to its genotype dependence and resource-intensive nature. Virus-induced gene editing (VIGE) has emerged as a promising approach, using plant viruses to deliver CRISPR reagents directly into plant tissues, thereby bypassing or minimizing tissue culture requirements. Although successful in model plants, adapting cowpea-compatible viral systems could accelerate genetic improvement and unlock its untapped potential.</p>

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Unlocking cowpea improvement: virus induced gene editing as a next-generation tool

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年7月3日

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  • Angela Sughnen,
  • Olakunle Sansa,
  • Michael Abberton

摘要

Cowpea is a vital grain legume in sub-Saharan Africa, providing affordable protein, essential micronutrients, and resilience in marginal environments. However, its genetic improvement is constrained by a narrow genetic base and limited introgression from wild relatives. Tissue culture remains a major bottleneck for deploying gene editing, due to its genotype dependence and resource-intensive nature. Virus-induced gene editing (VIGE) has emerged as a promising approach, using plant viruses to deliver CRISPR reagents directly into plant tissues, thereby bypassing or minimizing tissue culture requirements. Although successful in model plants, adapting cowpea-compatible viral systems could accelerate genetic improvement and unlock its untapped potential.