<p>Biorepositories with validated collection and preservation of biospecimens are crucial for biomarker and therapeutic discovery. Presently, multiple US federally funded, multicenter pancreatitis consortia studies maintain active biorepositories. The current study provides a comprehensive comparison of their collection methods and intended usage. Beyond each sample’s intended usage, these samples hold potential for novel applications based on emerging methodologies in the field. We anticipate that this review will provide useful information to help guide a consensus among pancreatitis consortium studies on optimal specimen collection and storage methods, which will further accelerate the tempo of discovery platforms in the pancreatitis space.</p>

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The emerging landscape of biorepositories among pancreatitis consortia studies in the US

  • Cordelia Li,
  • Dhiraj Yadav,
  • Mark E. Lowe,
  • Aliye Uc,
  • Maisam Abu-El-Haija,
  • Walter G. Park,
  • Bomi Lee,
  • Sohail Z. Husain

摘要

Biorepositories with validated collection and preservation of biospecimens are crucial for biomarker and therapeutic discovery. Presently, multiple US federally funded, multicenter pancreatitis consortia studies maintain active biorepositories. The current study provides a comprehensive comparison of their collection methods and intended usage. Beyond each sample’s intended usage, these samples hold potential for novel applications based on emerging methodologies in the field. We anticipate that this review will provide useful information to help guide a consensus among pancreatitis consortium studies on optimal specimen collection and storage methods, which will further accelerate the tempo of discovery platforms in the pancreatitis space.