<p>The liver, key for metabolism and homeostasis, sees growing focus on adrenergic GPCRs (α1/α2, β1/β2/β3; activated by adrenaline/noradrenaline). These receptors affect liver physiology/pathology and are treatment targets. This review explores their roles/mechanisms in liver diseases to aid research, clinic, and precise care.</p><p></p>

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Adrenergic G protein-coupled receptors in liver physiology and pathology: research advances and clinical implications

  • Yu Yang,
  • Yiwei Hou,
  • Yunxi Fu,
  • Li Yi,
  • Zhennian Gou,
  • Yashan Wang,
  • Yuxin Xue,
  • Jinting Xi,
  • Rongchun Xing,
  • Mingzheng Hu

摘要

The liver, key for metabolism and homeostasis, sees growing focus on adrenergic GPCRs (α1/α2, β1/β2/β3; activated by adrenaline/noradrenaline). These receptors affect liver physiology/pathology and are treatment targets. This review explores their roles/mechanisms in liver diseases to aid research, clinic, and precise care.