Scholarlink

<p>MicroRNAs are essential molecules that regulate many biological functions, including intestinal tight junction (TJ) barriers. They regulate pro-inflammatory cytokines, which increase TJ permeability, and anti-inflammatory cytokines, which protect against inflammation and promote intestinal balance. This review explores the role of miRNAs in controlling inflammation and as a potential therapeutic approach for treating IBD and other intestinal disorders. Circulating miRNAs can also serve as biomarkers for intestinal damage and disease progression.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

MicroRNA in intestinal tight junction regulation

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年5月5日

查看全文
  • Manmeet Rawat,
  • Prem Kumar Govindappa,
  • Yash Gupta,
  • Thomas Y. Ma

摘要

MicroRNAs are essential molecules that regulate many biological functions, including intestinal tight junction (TJ) barriers. They regulate pro-inflammatory cytokines, which increase TJ permeability, and anti-inflammatory cytokines, which protect against inflammation and promote intestinal balance. This review explores the role of miRNAs in controlling inflammation and as a potential therapeutic approach for treating IBD and other intestinal disorders. Circulating miRNAs can also serve as biomarkers for intestinal damage and disease progression.