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<p>Understanding the ways that mechanical stimuli influence tumour progression is vital for discovering treatments to overcome the limitations of current options. In this paper, the mathematical models used to quantify and explore the mechanical forces applied to cells and tissues are reviewed. Experiments that attempt to quantify the effects of mechanical stress on different stages of cancer are explored. Lastly, the biological effect of compression on cancer is discussed.</p>

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Mechanics and engineering models of tissue remodelling during tumour progression

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年7月6日

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  • Joshua Thiselton,
  • Pilnam Kim

摘要

Understanding the ways that mechanical stimuli influence tumour progression is vital for discovering treatments to overcome the limitations of current options. In this paper, the mathematical models used to quantify and explore the mechanical forces applied to cells and tissues are reviewed. Experiments that attempt to quantify the effects of mechanical stress on different stages of cancer are explored. Lastly, the biological effect of compression on cancer is discussed.