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<p>Tree roots sprouting into the ground or tumors proliferating within an organ are a few examples of proliferation under spatial confinement, which leads to growth-induced pressure. This compressive mechanical stress can impact a plethora of processes in all organisms. In this review, I will discuss the physiological and pathological consequences of spatial confinement in plants, microbes and animal cells, and will discuss in more depth the case of solid tumors.</p>

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Spatial confinement and life under pressure from physiology to pathology

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年3月5日

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  • Morgan Delarue

摘要

Tree roots sprouting into the ground or tumors proliferating within an organ are a few examples of proliferation under spatial confinement, which leads to growth-induced pressure. This compressive mechanical stress can impact a plethora of processes in all organisms. In this review, I will discuss the physiological and pathological consequences of spatial confinement in plants, microbes and animal cells, and will discuss in more depth the case of solid tumors.